Will you please try to answer these questions? They are due on Wed, October 27th. Thanks!,Thank you so much for helping me! THe answers were very easy to follow and understand. We have 2 more questions.. 8.32 and 8.33 to answer. I would really appreciate it if you can help me with these as well. One method for assessing the bioavailability of a drug is to note its concentration in blood and/or urine samples at certain periods of time after giving the drug. Suppose we want to compare the concentrations of two types of aspirin (types A and B) in urine specimens taken from the same person, 1 hour after he or she has taken the drug. Hence, a specific dosage of either type A or B aspirin is given at one time and the 1-hour urine concentration is measured. One week later, after the first aspirin has presumably been cleared from the system, the same dosage of the other aspirin is given to the same person and the 1 hour urine concentration is noted. Because the order of giving the drugs may affect the results, a table of random numbers is used to decide which of the two types of aspirin to give first. This experiment is performed on 10 people-results are given in the table. Person Aspirin A- 1 hour concentration (mg%) Aspirin B-1 hour concentration (mg%) 1 15 13 2 26 20 3 13 10 4 28 21 5 17 17 6 20 22 7 7 5 8 36 30 9 12 7 10 18 11 Mean 19.20 15.60 Standard deviation 8.63 7.78 8.31 What are the appropriate hypotheses? Here, we want to compare the concentrations of two types of aspirin (Types A and B). The specimens are taken from the same person, so paired t test would be appropriate. Let x1 and x2 be the concentration of Type A and Type B aspirin in Urine specimen in mg%. Let d = x1 - x2 Null Hypothesis Ho d = 0 Alternate Hypothesis H1 d ? 0 Level of significance ? 0.05 Decision rule- Reject Ho: If the absolute of calculated value is more than the critical value Value of the test statistic- Critical Value- Decision in terms of Ho -- At 5% level of significance, we reject the null hypothesis as the calculated value is more than the critical value Decision in terms of the problem-- At 5% level of significance, there is sufficient evidence to conclude that the mean concentration of Type A and Type B aspirin in urine specimen is significantly different. 8.32. What are the appropriate procedures to test these hypotheses? 8.33. Conduct the tests mentioned in problem 8.32. ( not sure if you did this already when you tested the hypothesis)???
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