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Whichofthefollowingareabsolutelyrequiredtoeradicateaviraldiseaseusingavaccination program

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hi rviswanathan;i need u to answer these question in the same level for last answer;Attachment Preview;PS14.docx Download Attachment;Question1;1.;Whichofthefollowingareabsolutelyrequiredtoeradicateaviraldiseaseusingavaccination;program(selecttwo)?;Answer;A Virusisonlyabletoinfecthumanhosts..;B. TheviraldiseasemustbecausedbyaRNAvirus;C. Thevaccinemustbeanattenuatedvirus;D Vaccineinduceslifelongimmunity..;E. ThevaccinemuststimulateTcells;2points;Question2;1.;Foravaccinetobeeffective,noteveryindividualinthepopulationneedbevaccinatedtostop;thespreadofthevirus.Thenumberofpeoplethatmustbevaccinatedtoproduceherdimmunity;iscalledtheherdimmunitythreshold.Theherdimmunitythresholdiscalculatedfromthebasic;reproductivenumberR0:whichistheaveragenumberofsecondaryinfectionsfromasingle;individualinfectedwithavirus.Calculatetheherdimmunitythresholdforthefollowingtwo;viruses;HumanPapillomaVirus(reproductivenumber=1.2)Blank1%;InfluenzaAVirus(reproductivenumber=4)Blank2%;Answer;2points;Question3;1.;Avaccineinwhichtheviralpolymeraseisdeletedwouldbeclassifiedasa(selectone)?;Answer;A ViruslikeParticleVaccine.;B. Attenuatedvaccine;C. Subunitvaccine;D.;Inactivatedvaccine;1points;Question4;1.;Geneticdriftandgeneticshiftaresignificantobstaclestothedevelopmentofvaccines;Answer;True;False;1points;Question5;1.;Brieflydescribewhyantiviraldrugstendtobeineffectiveagainstacuteviralinfections;Answer;PressTabtoenterthecontenteditor.Forthetoolbar,pressALT+F10(PC)orALT+FN+F10(Mac).;Path:p;Words:0;2points;Question6;1.;ManyofthedrugsusedtotreatHIVinhibitthesynthesisofnewviralgenomesfromthe;provirus?;Answer;True;False;1points;Question7;1.;IfresistancetotheHIVdrugLamuvidineoccursonceinevery10,000genomesproducedandresistancetotheproteaseinhibitor;Ritonaviroccursevery5,000genomesproduced,thenthelikelihoodofresistancedevelopingtobothdrugsis(selectone)?;Answer;1in5000;1in15,000;1in50,000,000;1in500,000;1in10,000;1points;Question8;1.;Matcheachofthefollowingdrugswiththestepinthevirallifecyclethattheyinhibit.;Answer;Oseltamavir;ReadAnswer;Itemsfor;Question8;Acyclovir;ReadAnswer;Itemsfor;Question8;Pleconaril;Answer;A.;Virus;Attachment;andEntry;B. VirusGenomeSynthesis;C. ViralProteinProcessing;D Virusexitandrelease.;ReadAnswer;Itemsfor;Question8;Ribavirin;ReadAnswer;Itemsfor;Question8;Telapravir;ReadAnswer;Itemsfor;Question8;Amantadine;ReadAnswer;Itemsfor;Question8;Zidovudine;ReadAnswer;Itemsfor;Question8;Maraviroc;ReadAnswer;Itemsfor;Question8;4points;Question9;1.;Oftheeightantiviraldrugslistedinthepreviousquestion,whichdrugisleastlikelytoleadto;viraldrugresistance?Why(34sentencesmax)?;Answer;PressTabtoenterthecontenteditor.Forthetoolbar,pressALT+F10(PC)orALT+FN+F10(Mac).;Path:p;Words:0;1points;Question10;1.;Therehasbeenmuchexcitementinrecentyearsabouttheuseofthedrugtenofovirointmentto;preventHIVinfectionsinwomen.Thegeneralclassofantiviraldrugsthatareadministeredas;eitheracreamorointmentthatcaninactivatevirionsorblocktheirabilitytoattachandpenetrate;tissuesarecalled[x]?;Answer;1points;Question11;1.;AnewantiviraldrugthattargetstheHepatitisCviruspolymerase(NS5B)isprescribedtoapatientwithsevereliver;disease.AfterafewweeksonthedrugthelevelofviralRNAintheblooddropsdramaticallyandthepatient'sliver;diseaseimproves.Aftersixmonths,thepatient'sviralloadincreasesdramaticallyandliverdiseasereturns.Provide;arationalexplanationforwhathasoccurredwiththispatient.Whattherapyordrugregimemighthaveprovideda;betterresult(limit56sentences)?;Answer;PressTabtoenterthecontenteditor.Forthetoolbar,pressALT+F10(PC)orALT+FN+F10(Mac).;Path:p;Words:0;2points;Question12;1.;If a single dose therapy could be developed that removed all infectious HIV viral particles (i.e.;virus genome surrounded by capsid and envelope) from a patient, would this result in a;functional cure such that the patient would not develop AIDs? Justify your answer in 3-5;sentences.;Answer;PressTabtoenterthecontenteditor.Forthetoolbar,pressALT+F10(PC)orALT+FN+F10(Mac).;Path:p;Words:0;2points

 

Paper#16698 | Written in 18-Jul-2015

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