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The Renin-Angiotensin-Aldosterone System (RAAS

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7. The Renin-Angiotensin-Aldosterone System (RAAS) is a key controller of blood pressure and sodium excretion. Explain;a. What is the pathway by which aldosterone is made from Angiotensinogen? Include all relevant steps and enzymes in this pathway.;b. Angiotensin II can regulate blood pressure in two ways, directly and indirectly. What are those two general mechanisms how Ang II plays a role?;c. Aldosterone acts on a longer term basis than does ADH. How does Aldosterone regulate water and sodium retention in the kidney? (include a discussion of how aldosterone works in the kidney, especially its role in regulating gene expression, and what part of the kidney aldosterone acts).;d. How would you expect aldosterone production to be differently regulated in our experimental conditions (hypo-, iso-, and hyper-tonic)?

 

Paper#16833 | Written in 18-Jul-2015

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