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STATS - A clinical trial is conducted comparing a new pain medication for arthritis

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Question;1. A clinical trial is conducted comparing a new pain medication for arthritis. Participants are randomly assigned to receive the new medication or a placebo. The outcome is pain relief within 30 minutes. The data are shown below.Pain Relief No Pain ReliefNew Medication 44 76Placebo 21 99Estimate the risk difference in pain relief between treatments=Estimate the relative risk in pain relief between treatments=Estimate the odds ratio in pain relief between treatments=The upper and lower limits of the are shown belowLower Limit of CI: _______Upper Limit of CI: ________Based on the Confidence Interval values which of the following are true?A. One can be 95% confident that the true value will be greater than the upper limit.B. One can be 95% confident that the true value will be greater than the lower limit.C. One can be 95% confident that the true value will between the upper and lower limit.D. a and b2. The following data were collected in a clinical trial evaluating a new compound designed to improve wound healing in trauma patients. The new compound is compared against a placebo. After treatment for 5 days with the new compound or placebo the extent of wound healing is measured and the data are shown below.Percent Wound HealingTreatment 0-25% 26-50% 51-75% 76-100%New Compound (n=125) 15 37 32 41Placebo (n=125) 36 45 34 10Is there a difference in the extent of wound healing by treatment? (Hint: Are treatment and the percent wound healing independent?) Run the appropriate test at a 5% level of significance.df= ________alpha= _______Reject H0 if?2> ________Compute expected frequenciesExpected Frequency = (Row Total * Column Total)/N.Complete the expected frequencies for each cell.Percent Wound Healing TotalTreatment 0-25% 26-50% 51-75% 76-100% New Compound 1537() 32() 41() 125Placebo 36(25.5) 45() 34() 10() 125Total 51 82 66 51 250Compute?2.?2= ______Based on comparing the computed?2 to the rejection level?2 which of the following is (are) true?A. We have statistically significant evidence at alpha=0.05 to show that H0 is false.B. Treatment and percent wound healing are not independent.C. Treatment and percent wound healing are independent.D. a and b.3. A clinical trial is conducted comparing a new pain reliever for arthritis to a placebo. Participants are randomly assigned to receive the new treatment or a placebo and the outcome is pain relief within 30 minutes. The data are shown below.Pain Relief No Pain ReliefNew Medication 44 76Placebo 21 99Is there a significant difference in the proportions of patients reporting pain relief? Run the test at a 5% level of significance.Reject H0 if Z ________alpha= ________= ________= ________= ________Z = _______Based on comparing the computed z to the rejection level z which of the following is (are) true?A. We have statistically significant evidence at alpha=0.05 to show that H0 is false.B. We have statistically significant evidence at alpha=0.05 to show that there a significant difference in the proportions of patients reporting pain relief.C. We do not have statistically significant evidence at alpha=0.05 to show there a significant difference in the proportions of patients reporting pain relief.D. a and b

 

Paper#61840 | Written in 18-Jul-2015

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